Aster Insights leads a collaborative network of cancer centers, researchers, industry partners, and patient advocates centered on the world's largest and longest running observational research study in oncology.


Total Cancer Care® is a unique and unprecedented research effort that is the foundation of data and evidence for Aster Insights’ solutions to accelerate the discovery of cancer cures:

  • Breadth of Data and Evidence: Total Cancer Care® is the largest and longest-running observational research study in oncology. TCC® includes patients with all cancer diagnoses, from early stage to advanced disease.
  • Lifetime Connection: Comprehensive and perpetual informed consent provides Aster Insights with unparalleled connection to any health information, including clinical data, molecular data, and tissue that fuel virtually any precision oncology research.
  • Diverse Demographics: Total Cancer Care® participants reflect the evolving diversity of America, including volunteers of all races and ethnicities, age groups, geographies, and health statuses.
  • Patient-Centric Research: Total Cancer Care® empowers participants by offering them a role in shaping research and sharing outcomes with them.
  • Specialized Data Collection: With a lifetime connection to patients’ health information, Aster Insights and ORIEN® concentrate on gathering data and biospecimens that are particularly relevant to cancer and its longitudinal effects on patients.
  • Actionable Data: Patients can be re-contacted for additional data or research opportunities, including clinical trial enrollment.
  • Data Accessibility: Total Cancer Care® data is broadly accessible to ORIEN® researchers for cancer-related research hypotheses.

Learn more at

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